Browser-based tools to explore how Ca2+ signals are generated, shaped and measured in neurons and glia.
Single-compartment model to explore how Ca2+ dynamics are shaped by homeostatic mechanisms and different Ca2+ indicators.
Visualise sub-membrane Ca2+ near an active zone with clustered channels. Change buffer and indicator properties to see how space shapes signal transduction.
Explore compartmentalised Ca2+ activity in astrocytic processes and endfeet, and how local events integrate over space and time.
Play with timing and voltage to see how NMDA receptors implement coincidence detection and shape Ca2+ entry into dendritic spines.
Learn how fluorescence lifetime encodes Ca2+ concentration and compare different indicators.
Simulate how scanning speed, dwell time and line geometry shape recorded Ca2+ signals in point- and line-scan imaging.
Learn how brain structure and device location can interact to affect electric fields from stimulation devices